FCGRT antibody {FITC}

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Catalog Number: orb156854-FITC

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Product Overview

Product Name	FCGRT antibody {FITC}
Catalog Number	orb156854-FITC
Species/Host	Rabbit
Reactivity	Human, Mouse, Rat
Predicted Reactivity	Canine, Sheep
Conjugation	FITC
Tested applications	ICC, IF
Immunogen	KLH conjugated synthetic peptide derived from the region aa61-140 of human FCGRT
Target	FCGRT
Alternative Names	(click to expand) anti-Alpha chain antibody, anti-Fc fragment of IgG, receptor transporter, alpha antibody, anti-FCGRN_HUMAN antibody, anti-FCGRT antibody, anti-FcRn alpha chain antibody, anti-FCRN antibody, anti-FCRN, alpha chain antibody, anti-IgG Fc fragment receptor transporter alpha chain antibody, anti-IgG Gc receptor antibody, anti-Immunoglobulin receptor, intestinal, heavy chain antibody, anti-Neonatal Fc receptor antibody, orb156854

Product Properties

Form/Appearance	Liquid: PBS(pH7.4)
Concentration	- 100 μg (in 522 μl): 0.19 mg/ml
Storage	Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note	For research use only.
Isotype	IgG
Clonality	Polyclonal
Purity	Affinity purified by Protein A
MW	37 kDa
Uniprot ID	P55899 (Human)
Entrez	2217

Product Description

Rabbit polyclonal antibody to FCGRT, which is also known as FCRN and neonatal Fc receptor. FCRN is a protein frequently found in the Single-pass type I membrane and is expressed in the uterus as well as hematopoietic bone marrow. It is overexpressed in spleen and nasopharynx. It extensively binds to the Fc region of monomeric immunoglobulins gamma i.e. IgG. IgG in milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids.

Application Notes